Valganciclovir for the prophylaxis and treatment of cytomegalovirus infection in solid organ transplantation
نویسندگان
چکیده
منابع مشابه
Human Cytomegalovirus Infection in Solid-Organ Transplantation
Human cytomegalovirus (CMV) continues to be a major threat against solid-organ transplant recipients despite significant advancements in its prophylaxis and therapy. Primary CMV infection or reactivation of latent CMV in the transplant recipients may cause CMV diseases such as flu-like viral syndrome and tissue-invasive CMV disease. In addition, CMV infection in the recipients is associated wit...
متن کاملCytomegalovirus infection in solid organ transplantation.
Cytomegalovirus infection remains a serious threat to solid transplant recipients. Despite advances in this field, there are still difficulties in the diagnosis of the disease and there are questions about the best and most cost-effective strategy to prevent infection and its direct and indirect consequences in the short and long term. All these points are discussed and updated in this chapter.
متن کاملManagement of cytomegalovirus infection and disease after solid-organ transplantation.
Cytomegalovirus (CMV) continues to be a cause of substantial morbidity and death after solid-organ transplantation. There are 3 major consequences of CMV infection: CMV disease, including a wide range of clinical illnesses; superinfection with opportunistic pathogens; and injury to the transplanted organ, possibly enhancing chronic rejection. This article discusses the considerable progress tha...
متن کاملEfficacy of Extended Valganciclovir Prophylaxis in Preventing Cytomegalovirus Infection in Pediatric Kidney Transplantation
Cytomegalovirus (CMV) is one of the most frequent opportunistic infection in renal transplant (RTx) recipients. Valganciclovir (VGC) has been showed to be safe and highly effective in prophylaxis of CMV infection in RTx recipients. Recently, an increase in delayed onset CMV disease has been noted with some arguing that longer prophylaxis may decrease the late-onset disease. We retrospectively t...
متن کاملefficacy of valganciclovir and ganciclovir for cytomegalovirus disease in solid organ transplants:a meta-analysis
background: cytomegalovirus (cmv), a problematic virus in solid organ transplant recipients (sotr) such as liver, can worsen overall mortality and transplant outcome, so its prevention and treatment is a key of success in such patients. this study is aimed to compare the efficacy of ganciclovir (gcv) and valganciclovir (vgc) for prevention and treatment of infection with cmv. materials and meth...
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ژورنال
عنوان ژورنال: Transplant Research and Risk Management
سال: 2010
ISSN: 1179-1616
DOI: 10.2147/trrm.s5979